Newsletter No. 10. June, 2005




Honorary President: Prof. Dr.Dr.h.c. Franz Gerstenbrand (Vienna); Secretary General: Prof. Dr. László Vécsei (Szeged)

Deputy Secretary General: Prof. Dr. Zbigniew Stelmasiak (Lublin); Scientific Secretary: Prof. Dr. Gerhard Ransmayr (Linz)

Coordinator: Assoc. Prof. Dr. János Tajti (Szeged); Head of Office: Assoc. Lecturer Erika Grossmann (Szeged)


1. Jubilee number of the DANUBE NEUROLOGY NEWSLETTER

2. Preliminary Scientific Programme of the 37th International Danube Association – with the 21st Dr. Janez Faganel Memorial Lecture

3. Future Conferences, Meetings, Courses and Symposia

4. Present and Future Activities of the International Danube Neurology Association

5. WFN – Future Tasks and Obligations (by: Franz Gerstenbrand, Vienna, Austria)

6. Harmonization of PhD-Programs in Medicine and Health

7. Finances of the International Danube Neurology Association

8. Web-site of the International Danube Neurology Association


1. Jubilee number of the DANUBE NEUROLOGY NEWSLETTER

It is our great pleasure that we can announce you the jubilee number of the DANUBE NEUROLOGY NEWSLETTER, edited by the Head Office of the International Danube Neurology Association in Szeged, Hungary!

The first Danube Neurology Newsletter has been compiled in November 2000, and since then, every year two numbers have been edited and sent to almost 600 addresses, and the electronic version is available free of charge on Internet as well.

2. Preliminary Scientific Programme of the 37th International Danube Neurology Symposium

- with the 21st Dr. Janez Faganel Memorial Lecture

We would like to draw your attention to the next Danube Neurology Symposium in Ljubljana, Slovenia

from 5-8 October, 2005.

Below you find some important information about the Meeting and please visit the website of the Symposium for detailed information, registration and accommodation:


Symposium office: Auditoria d.o.o., Mrs. Irena Jelen
Malnarjeva 10, SI-1000 Ljubljana, Slovenia
Phone: + 386 1 36-55-252, Fax: + 386 1 36-37-345 E-mail: irena.jelen@auditoria.si

Venue: Hotel Mons (Address: Pot za Brdom 55, SI-1000 Ljubljana, Slovenia)
Phone: +386 1 420-27-11, Fax: +386 1 420-27-08 e-mail: info@hotel.mons.si http://www.hotel.mons.si



Symposium website: http://auditoria.si/danube2005/index.htm





WEDNESDAY, October 5, 2005

Satellite 'Stroke Symposium'

10.30–10.40 Opening – A. Członkowska, B. Žvan

10.40–13.00 Management of acute ischaemic stroke

10.40–11.10 N. G. Walghren (Stockholm, Sweden): Thrombolysis – SITS: the case for safety monitoring during broad implementation of thrombolysis

11.10–11.40 G. S. Venables (Sheffield, United Kingdom): Fibrinolytic therapy in patients with acute ischaemic stroke (IST-3 Study)

11.40–12.10 M. Grobovschek (Salzburg, Austria): Early neuroimaging changes in patients with acute ischaemic stroke

12.10–13.00 Round table with short communications: Fibrinolytic therapy in Danube countries

A. Członkowska (Warsaw, Poland)

N. G. Walghren (Stockholm, Sweden)

G. S. Venables (Sheffield, United Kingdom)

V. Švigelj (Ljubljana, Slovenia)

Representatives from different countries


13.00–15.00 Lunch

13.00–13.30 CEESS Meeting – General Assembly

15.00–18.00 Carotid stenting

15.00–15.20 V. Demarin (Zagreb, Croatia): Pathophysiology and diagnosis of carotid disease

15.20–15.40 M. Zaletel (Ljubljana, Slovenia): Carotid stenting studies

15.40–16.00 G. E. Klein (Graz, Austria): Future horizon of arteries’ stenting in neurology

16.00–16.30 B. Žvan (Ljubljana, Slovenia): Selection of the patients for carotid stenting

16.30–17.00 Z. Miloševič, I. Kocijančič (Ljubljana, Slovenia): Carotid stenting procedure, our experiences

17.00–18.00 Round table: Carotid stenting in Danube countries

K. Niederkorn (Graz, Austria)

V. Demarin (Zagreb, Croatia)

G. E. Klein (Graz, Austria)

Z. Miloševič (Ljubljana, Slovenia)

B. Žvan (Ljubljana, Slovenia)

Representatives from different countries

18.00–18.15 Poster highlights

U. Rot (Ljubljana, Slovenia), R. Herzig (Olomouc, Czech Republic)

20.00 Get-together

THURSDAY, October 6, 2005

08.15–08.30 Opening ceremony

08.30–09.05 J. Faganel Memorial Lecture:

T. Prevec (Ljubljana, Slovenia): Sharp or kind stimulus to activate the sensory system

09.05–09.15 Coffee break

09.15–11.15 Parallel session A: Pathophysiology of cortical motor disorders

P. Battaglini (Trieste, Italy): Physiological mechanisms of cortical motor system

T. Shallice (Trieste, Italy, and London, United Kingdom): Apraxias

V. Kostić (Belgrade, Serbia and Montenegro): Dystonia

P. Klivenyi (Szeged, Hungary): Akinesia and motor neglect

G. Pfurtscheller (Graz, Austria): Electroencephalographic evaluation of cortical motor functions

09.15–11.15 Parallel session B: Functional neuroimaging

A. Barnes (New York, USA): What is functional neuroimaging? Basic principles of SPECT, PET and fMRI imaging methods

J. Booij (Amsterdam, The Netherlands): SPECT in neurology: is it useful in clinical practice?

D. Brooks (London, UK): The use of PET in Parkinson's disease and dementia

J. Krakauer (New York, USA): What have we learned about stroke recovery from functional imaging?

11.1511.30 Coffee break

11.3012.30 Satellite symposium on new diagnostic and treatment aspects of neurological disorders

M. Bojar (Prague, Czech Republic): DAT scan & parkinsonism

S. Šega (Ljubljana, Slovenia): Different IFN-beta have different patterns of influence on cytokines

G. Comi (Milano, Italy): Optimizing MS treatment: importance of long term efficacy and safety data

12.3013.15 Poster highlights

U. Rot (Ljubljana, Slovenia), R. Herzig (Olomouc, Czech Republic)

13.15–14.30 Lunch

14.30–16.15 Parallel session A: Recent findings in experimental and clinical neurology

H. Reichmann (Dresden, Germany): Role of mitochondrial dysfunctions in neurological disorders

L. Vecsei (Szeged, Hungary): Mitochondrial toxins and the kynurenine system: therapeutic considerations

F. Bajrović (Ljubljana, Slovenia): Collateral sprouting of sensory axons after peripheral nerve injury

H. Kingma (Maastricht, The Netherlands): New frontiers in vertigo

14.30–16.15 Parallel session B: Neurodegenerative disorders

D. Flisar (Maribor, Slovenia): Update on tremor

E. Ott (Graz, Austria): Update on dystonia

M. Bareš (Minneapolis, USA): Update on spinocerebellar ataxias

H. Reichmann (Dresden, Germany): Role of pramipexole in Parkinson's disease patients with depressive mood

16.15–16.30 Coffee break

16.30–17.30 Parallel session A: Hand-over clinics – Transition from paediatric to adult neurology

R. Appleton (Liverpool, United Kingdom): »Handing-over« patients with neurological disorder from paediatric to adult institution (general problems, British examples, joint clinics)

V. Komarek, P. Marusic (Prague, Czech Republic): Handing-over patients with epilepsy in Prague

16.30–17.30 Parallel session B: Specialist nurses in neurology

K. Turner (London, UK): Specialist nurses in neurology

L. Ocepek (Ljubljana, Slovenia): Specialist nurse in parkinsonism

D. Zengerle (Prague, Czech Republic): The role of MS nurse in patient adherence

17.30–18.30 Satellite symposium on the use of botulinum toxin in neurology

20.30 Basal ganglia video dinner

FRIDAY, October 7, 2005

08.30–09.30 Personal neurological letters from Danube countries & beyond

letter from Austria (G. Ransmayr)

letter from Slovenia (D. B. Vodušek)

letter from Iran (B. Mansouri)

09.30–11.00 Parallel session A: Paediatric neurological disorders at the end of adolescence

M. Macedoni-Lukšič (Ljubljana, Slovenia): Autistic syndromes

V. Farkas (Budapest, Hungary): Migraine – appropriate diagnostics and treatment in adolescents

M. Žerjav-Tanšek (Ljubljana, Slovenia): Inborn errors of metabolism – what is the outcome during late adolescence?

09.30–11.00 Parallel session B: Migraine

P. Stribos (London, UK) : New emerging technologies for the treatment of migraine

B. Žvan, M. Zaletel, T. Pogačnik (Slovenia): Classification, patophysiology and treatment of migraine

R. Agosti (Zurich, Switzerland): New triptan studies

11.00.–11.15 Coffee break

11.15–12.15 Satellite symposium on a new option in migraine prevention

12.15–13.15 Satellite symposium on treatment of dementia and depression (KRKA)

13.1513.45 Poster highlights

U. Rot (Ljubljana, Slovenia), R. Herzig (Olomouc, Czech Republic)

13.45–15.00 Lunch

15.00–17.00 Parallel session A: Demyelinating disease

F. Deisenhammer (Innsbruck, Austria): Update on neutralising antibodies: the Austrian perspective

H. Lassman (Vienna, Austria): A more detailed discussion on primary progressive MS in relation to other forms of MS

Z. Stelmasiak (Lublin, Poland): Differential diagnosis of MS

V. Brinar (Zagreb, Croatia): Non-MS recurrent demyelinating diseases

15.00–17.00 Parallel session B: Bridging neurology & psychiatry

A. Korczyn (Tel Aviv, Israel): Where is pain in the brain

Z. Pirtošek (Ljubljana, Slovenia): Neurology of free will

Round table on bridging neurology and psychiatry

N. Homann (Graz, Austria), M. Kocmur (Ljubljana, Slovenia)

A. Korczyn (Tel Aviv, Israel), I. Rektor (Brno, Czech Republic)

M. Relja (Zagreb, Croatia). V. Kostić (Beograd, Serbia and Montenegro), D. B. Vodušek (Ljubljana, Slovenia)

17.00–17.15 Coffee break

17.15–18.15 Satellite symposium on MS treatment

17.1519.15 Young neurologists’ (YNT) get-together

20.30 Gala dinner



SATURDAY, October 8, 2005


08.30–09.15 Danube Lecture:

V. V. Dolenc: Role of neurosurgery in neuroscience, daily practice and research

09.15–10.45 Ethical issues in neurology

(End of life decisions, Authorisation and

consent in paediatric treatment, Questions

and issues from the audience)

J. Trontelj (Ljubljana, Slovenia)

F. Gerstenbrand (Vienna, Austria)

G. Virt (Vienna, Austria)

R. Kurz (Graz, Austria) or H. Baumgartner (Innsbruck, Austria)

10.45–11.00 Coffee break

11.00–13.00 Polyneuropathies

W. Grisold (Vienna, Austria): Clinical approach to polyneuropathies

J. Zidar (Ljubljana, Slovenia): Electromyographic diagnosis of polyneuropathies

S. Apostolski (Belgrade, Serbia & Montenegro): Immunology of polyneuropaties – diagnostic applications

L. Leonardis (Ljubljana, Slovenia): Genetic polyneuropathies

T. Roš (Ljubljana, Slovenia): Paraneoplastic polyneuropathies

13.00 Closing the Symposium


3. Future Meetings of the International Danube Neurology Association

3.1 The 38th International Danube Neurology Symposium

Venue: Brno, Czech Republic Hotel Voronez****.

Date: 6-8 April, 2006

Main topics: Epilepsy; Movement Disorders; Cognitive Disorders; Stroke; further topics in discussion.

Teaching Courses: Epilepsy; Movement Disorders; Cognitive Disorders; further topics in discussion.

Chairman of Organizing Committee: Prof.Dr. Ivan Rektor; e-mail address: irektor@med.muni.cz

Symposium Organiser: TA-Service, Mgr. Ivana Tarabová

Hlinky 48, 603 00 Brno, Czech Republic

Tel./Fax: +420 543 211 134

Further information under: www.ta-service.cz/danube and tarabova@traveller.cz

3.2 The 39th International Danube Neurology Symposium in conjunction with the

1st International Congress on ADHD: from childhood to adult disease

Venue: Congress Center of Würzburg, Germany Time: June 3-7, 2007

For further information, please contact the Organizer: Prof. Dr. Peter Riederer

e-mail address: peter.riederer@mail.uni-wuerzburg.de

Phone: +49-931-201-77200, Fax: +49-931-201-77220


3.3 Applicants for the International Danube Neurology Symposium in 2008, 2009 and 2010

Present applicants for the future International Danube Neurology Symposia are: 1) Bucuresti, Romania 2) Linz, Austria and 3) Zagreb, Croatia.

The decision about final applicants will be at the Curatorium Meeting of the IDS in Ljubljana, Slovenia (5-8th October, 2005).

3.4 Danube Neurology Teaching Course on Epilepsy, Migraine and Neurosonology

Venue: To be held in Kazimierz, Poland Time: May 2006.

Main topics: Epilepsy, Migraine and Neurosonology

Chairman of Organizing Committee: Prof. Z. Stelmasiak e-mail: neurolog@asklepios.am.lublin.pl


4. Present and Future Activities of the International Danube Neurology Association

  • The Danube Neurology Association fosters and coordinates fellowship programs for young neurologists from Danube Countries

  • Coordination of future Danube Neurology Symposia

  • The Danube Neurology Neurology Newsletter is posted to more than 600 surface addresses, and the electronic version is available free of charge on Internet as well;

  • We also consider as our task to help with the activity of the EFNS in the Danube-countries.



5. WFN – Future Tasks and Obligations (compiled by: Franz Gerstenbrand, Vienna, Austria)

Neurology in West Europe using most modern technology and high advanced biochemistry and molecular genetics has an immense development.

In human brain structural and functional disturbances can be discovered. Great advances were possible in the treatment of stroke, dementia, epilepsy and degenerative diseases of the nervous system. The second leg in Neurology, the field of Neuro-Rehabilitation is beginning to be spread out, specialized centers are continously built up, thus reducing disability and chronic acute damage to the brain and spinal cord. The problem however is, that all these progresses in diagnostic and treatment are very expensive. Parallel with the great progress, Neurology lost influence and responsibility for pain, traumatic brain and spinal cord injury, vascular disorders including stroke and therapy in neurologic conditions invertible spine disturbances.

A crucial point is that only a minor part of human society is participating on the progress in Neurology and the extraordinary results are only reaching a small part of the world. There is no neurology




in most of the black Africa and Central Asia Regions; the field of Neurology is not well-organized and only partly equipped neurological centers are existing in South East Asia, some regions of East Europe, in the Middle East countries and in Latin America. To be only a consultant in Neurology provides great limits in the best care for patients. Unfortunately most neurological patients are treated poorly by physicians without specialized knowledge of the nervous system. There are no plans available for the organization of sufficient health system or long-lasting treatment programs for Neurology. In addition, a diminution of neurological service can be found in East Europe, North and South Africa and Latin America.

World-wide no demand exists that every patient with a disease of the nervous system should have the basic human right to be diagnosed and receive thorough treatment in a specialized neurological department and to run a neuro-rehabilitation in specialized neurological centers. However sometimes patients are satisfied to get treatment and care in a more or less organized hospital. This situation bothered financially weak patients in western countries too. To refuse the treatment of aged people or chronic neurological condition in some European countries has to be called an unethical decision.

The World Federation of Neurology needs to centralize and adapt his program to black Africa, South East Asia and in other parts of the world, with the aim to assist the building up of national institutions and societies for Neurology. Support is necessary in information for neurology for the local health care system and to enthusiast young medical doctors to become a specialist in neurology. Teaching courses should be organized as well as neurological days during national medical congresses and meetings. Bedside teaching could be organized by visiting professors. To send medical books and periodicals for the training of neurologists is only a first step, but it is not a substitute for better diagnostic programs and successful treatment. A cooperation with the WHO and NGO’s is helpful. An important step would be to find the local needs and to resolve them.

The World Federation of Neurology as the responsible institution has to start new actions for this obligations as a real step to a modern care in Neurology. A group of experienced neurologists should support and coordinate this program. A cooperation with the WHO would be helpful, but with the knowledge, that this governmental organization has lack of money and in some of the developing countries WHO has not the right resonance because of ignoring local problems.

The incoming president must face these urgent obligations and he or she must use as much energy as to attend regional meetings and to prepare for a world congress.

6. Harmonization of PhD-Programs in Medicine and Health Sciences


The curriculum proposal for university interdisciplinary PhD-program in neuroscience has been worked under the coordination of the Faculty of Medicine of the University of Zagreb with the cooperation of a great number of European Committees on the harmonization of PhD-Programs in Medicine and Health Sciences. The additional proposal by the Department of Neurology, Albert Szent-Györgyi Medical and Pharmaceutical Center, Faculty of Medicine, University of Szeged is the following:

The PhD-thesis should be based on original in extenso publications in internationally recognized scientific medical journals. It is important, that the minimal requirement for the PhD-thesis application in neuroscience should be the equivalent of at least three in extenso papers published in internationally recognized journals.

According to the present practice in the PhD-Programs in Medicine and Health Sciences in Szeged, the median impact

in neurology:

1.4, therefore 2.5x1.4=3.5

in psychiatry:

1.3, therefore 2.5x1.3=3.25

in neurobiology:

1.8, therefore 2.5x1.8=4.5

cumulative impact factor is necessary for the application of a PhD-thesis.


7. Finances of the International Danube Neurology Association

According to previous decision of the Danube Curatorium Meeting, the financial sources of the International Danube Neurology Association from all kinds of symposia, conferences, meetings or courses under the roof and auspices of our organization, are as follows: The financial surplus of all meetings should be divided 70:30 between the Local Organizers and the permanent International Danube Neurology Symposium Head Office in Szeged, Hungary or the amount of min. EUR 2,500 is to be transferred to the Head Office according to our invoice.


8. Web-site of the International Danube Neurology Association

The home-page of the International Danube Neurology Association consists of:

  • the contents of all Newsletter (Nr.1-10)
  • Managing and Executive Board Members of Danube Neurology Association
  • Past and future Symposia, Conferences, Meetings
  • Other further important information.







Danube Association web-site: